You're describing a specific chemical compound, and while I can analyze its structure and provide some general information, I can't tell you its exact importance in research without more context. Here's why:
**Understanding the Compound**
* **Structure:** The name describes a complex organic molecule with several functional groups:
* **Pyridazinecarboxylic acid methyl ester:** This indicates a core pyridazine ring (a six-membered heterocycle containing nitrogen atoms) with a carboxylic acid group and a methyl ester attached.
* **1-(4-methoxyphenyl):** A 4-methoxyphenyl group (a benzene ring with a methoxy group at the 4th position) is attached at the 1st position of the pyridazine ring.
* **4-[(4-methylphenyl)thio]:** A 4-methylphenyl group (a benzene ring with a methyl group at the 4th position) is attached at the 4th position of the pyridazine ring, connected via a sulfur atom (thio).
* **6-oxo:** An oxygen atom is double-bonded to the 6th carbon atom of the pyridazine ring.
* **Potential Properties:** This compound likely exhibits properties related to its chemical structure:
* **Biological activity:** The presence of aromatic rings and heterocycles suggests potential interactions with biological systems, possibly with enzyme activity or receptor binding.
* **Pharmacological interest:** The structure contains elements often found in drugs, making it a candidate for drug discovery research.
* **Synthesis and Chemistry:** Its unique structure may be interesting for synthetic chemists to study and modify.
**Why Importance Is Contextual**
The importance of this compound in research depends on various factors:
* **Specific Research Area:** Is it being investigated as a potential drug candidate? Is it a building block for synthesizing other compounds? Is it a probe for studying enzyme activity?
* **Research Findings:** Has the compound been shown to have interesting biological effects or unique chemical properties?
* **Published Literature:** Has this compound been previously studied and published in scientific journals?
**How to Find More Information**
To learn more about the compound's importance, you'd need to:
1. **Search Scientific Databases:** Use databases like PubMed, SciFinder, or Reaxys to find relevant research articles that mention the compound's name or its chemical structure.
2. **Consult Experts:** Reach out to researchers in the relevant field to see if they are familiar with this compound and its significance.
Please provide more context about the compound's purpose or its research background, and I can try to give you a more specific answer.
ID Source | ID |
---|---|
PubMed CID | 3313569 |
CHEMBL ID | 1455223 |
CHEBI ID | 109563 |
Synonym |
---|
HMS2630E06 |
methyl 1-(4-methoxyphenyl)-4-[(4-methylphenyl)sulfanyl]-6-oxo-1,6-dihydro-3-pyridazinecarboxylate |
smr000333379 |
MLS000696256 |
BIONET1_000467 |
OPREA1_544060 |
CHEBI:109563 |
HMS569D09 |
AKOS005084642 |
methyl 1-(4-methoxyphenyl)-4-(4-methylphenyl)sulfanyl-6-oxopyridazine-3-carboxylate |
methyl 1-(4-methoxyphenyl)-4-[(4-methylphenyl)sulfanyl]-6-oxo-1,6-dihydropyridazine-3-carboxylate |
2F-065 |
338395-97-4 |
CHEMBL1455223 |
Q27188705 |
1-(4-methoxyphenyl)-4-[(4-methylphenyl)thio]-6-oxo-3-pyridazinecarboxylic acid methyl ester |
methyl1-(4-methoxyphenyl)-4-[(4-methylphenyl)sulfanyl]-6-oxo-1,6-dihydropyridazine-3-carboxylate |
Class | Description |
---|---|
aryl sulfide | Any organic sulfide in which the sulfur is attached to at least one aromatic group. |
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res] |
Protein | Taxonomy | Measurement | Average (µ) | Min (ref.) | Avg (ref.) | Max (ref.) | Bioassay(s) |
---|---|---|---|---|---|---|---|
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE | Homo sapiens (human) | Potency | 0.0035 | 0.0032 | 45.4673 | 12,589.2998 | AID2517 |
Chain A, Beta-lactamase | Escherichia coli K-12 | Potency | 0.7079 | 0.0447 | 17.8581 | 100.0000 | AID485294 |
USP1 protein, partial | Homo sapiens (human) | Potency | 17.7828 | 0.0316 | 37.5844 | 354.8130 | AID743255 |
aldehyde dehydrogenase 1 family, member A1 | Homo sapiens (human) | Potency | 22.3872 | 0.0112 | 12.4002 | 100.0000 | AID1030 |
geminin | Homo sapiens (human) | Potency | 6.5131 | 0.0046 | 11.3741 | 33.4983 | AID624296 |
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023] |
Assay ID | Title | Year | Journal | Article |
---|---|---|---|---|
AID588499 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set | 2010 | Current protocols in cytometry, Oct, Volume: Chapter 13 | Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening. |
AID588499 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set | 2006 | Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5 | Microsphere-based protease assays and screening application for lethal factor and factor Xa. |
AID588499 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set | 2010 | Assay and drug development technologies, Feb, Volume: 8, Issue:1 | High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors. |
AID588501 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set | 2010 | Current protocols in cytometry, Oct, Volume: Chapter 13 | Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening. |
AID588501 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set | 2006 | Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5 | Microsphere-based protease assays and screening application for lethal factor and factor Xa. |
AID588501 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set | 2010 | Assay and drug development technologies, Feb, Volume: 8, Issue:1 | High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors. |
AID504812 | Inverse Agonists of the Thyroid Stimulating Hormone Receptor: HTS campaign | 2010 | Endocrinology, Jul, Volume: 151, Issue:7 | A small molecule inverse agonist for the human thyroid-stimulating hormone receptor. |
AID651635 | Viability Counterscreen for Primary qHTS for Inhibitors of ATXN expression | |||
AID504810 | Antagonists of the Thyroid Stimulating Hormone Receptor: HTS campaign | 2010 | Endocrinology, Jul, Volume: 151, Issue:7 | A small molecule inverse agonist for the human thyroid-stimulating hormone receptor. |
AID1745845 | Primary qHTS for Inhibitors of ATXN expression | |||
AID588497 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set | 2010 | Current protocols in cytometry, Oct, Volume: Chapter 13 | Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening. |
AID588497 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set | 2006 | Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5 | Microsphere-based protease assays and screening application for lethal factor and factor Xa. |
AID588497 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set | 2010 | Assay and drug development technologies, Feb, Volume: 8, Issue:1 | High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors. |
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |
Timeframe | Studies, This Drug (%) | All Drugs % |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 1 (20.00) | 29.6817 |
2010's | 3 (60.00) | 24.3611 |
2020's | 1 (20.00) | 2.80 |
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.
| This Compound (12.56) All Compounds (24.57) |
Publication Type | This drug (%) | All Drugs (%) |
---|---|---|
Trials | 0 (0.00%) | 5.53% |
Reviews | 0 (0.00%) | 6.00% |
Case Studies | 0 (0.00%) | 4.05% |
Observational | 0 (0.00%) | 0.25% |
Other | 5 (100.00%) | 84.16% |
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |